With the advent of climate change, new microbiological threats are emerging that can threaten food safety and quality, lead to environmental degradation and have an overall negative impact on human health. In addition, the increase in microbial resistance, such as multidrug resistance, antifungal tolerance and similar trends in emerging microbial pathogens, are a serious global problem due to anthropogenic activities and climate-induced temperature changes in recent years.

To effectively address, avoid and correct the negative impacts of these emerging microbial threats on ecosystems and human health, it is necessary to adopt a holistic and interdisciplinary One Health approach, taking into account the complex and interdependent relationships among humans, plants, animals and microbes. To achieve the goal of One Health, it is essential to study and understand emerging and new microbial threats and urgently establish comprehensive monitoring systems to detect these threats in advance, enabling timely and effective responses. Furthermore, it is crucial to develop sound management strategies to mitigate their cumulative impacts on the environment and human health. Such strategies should include preventive measures, rapid response protocols and long-term management plans tailored to specific ecosystems and microbial threats. Therapeutic interventions also play an important role in this holistic approach, and new treatments and therapies can help prevent infections and diseases caused by emerging pathogens, thereby protecting food production, environmental sustainability and public health. Combining routine monitoring, sustainable management and therapeutic strategies will allow us to build a resilient framework that protects our ecosystems and ensures a healthier future for all living organisms.

This proposed research topic welcomes high-quality research articles and reviews on new emerging microbial threats from various natural ecosystems, such as agriculture and aquatic environments. We also encourage submission of manuscripts discussing microbial pathogenicity, therapeutic interventions, and innovative strategies to combat emerging microbes, including microbial

drug resistance. In addition, comprehensive epidemiological studies on cross-transmission of pathogenic strains from hospitals, animal husbandry and other industries will be appreciated.

This theme is dedicated to supporting research that addresses current challenges and anticipates future goals, advocating for a holistic and integrated approach to environmental and public health. All submissions are likely to stimulate transformative ideas that offer significant conceptual advances in the field.

Keywords: Microbiome; Emerging bacterial pathogens; Candida auris; Aspergillus; Protists; Phage therapy; Antibiotic, antifungal and multidrug resistance; Biofilm; Quorum sensing and quenching; One Health

Important note: All work within this Research Topic must be within the scope of the section and journal to which it is submitted, as defined in their mission statements. Frontiers reserves the right to refer an out-of-scope manuscript to a more appropriate section or journal at any stage of peer review.

With the advent of climate change, new microbiological threats are emerging that can threaten food safety and quality, lead to environmental degradation and have an overall negative impact on human health. In addition, the increase in microbial resistance, such as multidrug resistance, antifungal tolerance and similar trends in emerging microbial pathogens, are a serious global problem due to anthropogenic activities and climate-induced temperature changes in recent years.

To effectively address, avoid and correct the negative impacts of these emerging microbial threats on ecosystems and human health, it is necessary to adopt a holistic and interdisciplinary One Health approach, taking into account the complex and interdependent relationships among humans, plants, animals and microbes. To achieve the goal of One Health, it is essential to study and understand emerging and new microbial threats and urgently establish comprehensive monitoring systems to detect these threats in advance, enabling timely and effective responses. Furthermore, it is crucial to develop sound management strategies to mitigate their cumulative impacts on the environment and human health. Such strategies should include preventive measures, rapid response protocols and long-term management plans tailored to specific ecosystems and microbial threats. Therapeutic interventions also play an important role in this holistic approach, and new treatments and therapies can help prevent infections and diseases caused by emerging pathogens, thereby protecting food production, environmental sustainability and public health. Combining routine monitoring, sustainable management and therapeutic strategies will allow us to build a resilient framework that protects our ecosystems and ensures a healthier future for all living organisms.

This proposed research topic welcomes high-quality research articles and reviews on new emerging microbial threats from various natural ecosystems, such as agriculture and aquatic environments. We also encourage submission of manuscripts discussing microbial pathogenicity, therapeutic interventions, and innovative strategies to combat emerging microbes, including microbial

drug resistance. In addition, comprehensive epidemiological studies on cross-transmission of pathogenic strains from hospitals, animal husbandry and other industries will be appreciated.

This theme is dedicated to supporting research that addresses current challenges and anticipates future goals, advocating for a holistic and integrated approach to environmental and public health. All submissions are likely to stimulate transformative ideas that offer significant conceptual advances in the field.

Keywords: Microbiome; Emerging bacterial pathogens; Candida auris; Aspergillus; Protists; Phage therapy; Antibiotic, antifungal and multidrug resistance; Biofilm; Quorum sensing and quenching; One Health

Important note: All work within this Research Topic must be within the scope of the section and journal to which it is submitted, as defined in their mission statements. Frontiers reserves the right to refer an out-of-scope manuscript to a more appropriate section or journal at any stage of peer review.